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Environmental concerns have prompted the Chinese government to enforce strict regulations on the titanium dioxide industry. Manufacturers are compelled to adopt cleaner production methods and waste management strategies to minimize the environmental footprint. Additionally, there is a growing trend towards the use of recycled titanium dioxide, reducing the reliance on raw materials and further contributing to sustainability efforts Additionally, there is a growing trend towards the use of recycled titanium dioxide, reducing the reliance on raw materials and further contributing to sustainability efforts Additionally, there is a growing trend towards the use of recycled titanium dioxide, reducing the reliance on raw materials and further contributing to sustainability efforts Additionally, there is a growing trend towards the use of recycled titanium dioxide, reducing the reliance on raw materials and further contributing to sustainability effortschina 6618 titanium dioxide.

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Titanium dioxide (TiO2) is commonly applied to enhance the white colour and brightness of food products. TiO2 is also used as white pigment in other products such as toothpaste. A small fraction of the pigment is known to be present as nanoparticles (NPs). Recent studies with TiO2 NPs indicate that these particles can have toxic effects. In this paper, we aimed to estimate the oral intake of TiO2 and its NPs from food, food supplements and toothpaste in the Dutch population aged 2 to over 70 years by combining data on food consumption and supplement intake with concentrations of Ti and TiO2 NPs in food products and supplements. For children aged 2-6 years, additional intake via ingestion of toothpaste was estimated. The mean long-term intake to TiO2 ranges from 0.06 mg/kg bw/day in elderly (70+), 0.17 mg/kg bw/day for 7-69-year-old people, to 0.67 mg/kg bw/day in children (2-6 year old). The estimated mean intake of TiO2 NPs ranges from 0.19 μg/kg bw/day in elderly, 0.55 μg/kg bw/day for 7-69-year-old people, to 2.16 μg/kg bw/day in young children. Ninety-fifth percentile (P95) values are 0.74, 1.61 and 4.16 μg/kg bw/day, respectively. The products contributing most to the TiO2 intake are toothpaste (in young children only), candy, coffee creamer, fine bakery wares and sauces. In a separate publication, the results are used to evaluate whether the presence of TiO2 NPs in these products can pose a human health risk.

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Today, TiO2 factories employ advanced technologies and rigorous quality control measures to ensure consistent product quality and minimize environmental harm. They also invest in research and development to improve production efficiency and explore new applications for titanium dioxide. For example, some factories have developed nano-sized TiO2 particles that exhibit enhanced UV-blocking properties, making them ideal for use in sunscreens and cosmetics For example, some factories have developed nano-sized TiO2 particles that exhibit enhanced UV-blocking properties, making them ideal for use in sunscreens and cosmetics For example, some factories have developed nano-sized TiO2 particles that exhibit enhanced UV-blocking properties, making them ideal for use in sunscreens and cosmetics For example, some factories have developed nano-sized TiO2 particles that exhibit enhanced UV-blocking properties, making them ideal for use in sunscreens and cosmeticstinox tio2 factories.

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Macromolecular oxidation was detected in proteins by the colorimetric measurement of Advanced Oxidation Protein Products (AOPP) and in lipids by the colorimetric quantification of malondialdehyde (MDA). Standard curves were run with chloramine-T and 1,1,3,3 tetraethoxypropane (TEP) for AOPP and MDA methods, respectively [29][30][31]. Values were normalized to initial protein content in samples, measured with Bradford reagent [32]. The standard deviation of at least six measures was calculated and p-value < 0.05 were considered significant.

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